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Recombinant origin of the XMRV sequence [2]. The preXMRV-1 and preXMRV-2 genomes with their homology to the XMRV consensus sequence are shown. Template switching events indicated with blue arrows occurred in regions of 20–73 nucleotide identity between both viral RNAs. Nucleotide numbers refer to 22Rv1 XMRV (Acc. No. FN692043). Six template switching events result in a sequence differing from all known XMRV isolates by only 4–13 nucleotides.
