Table 3. Association between alcohol consumption and breast cancer risk.
| No. cases/controls | OR (95% CI) a | P-value | |
|---|---|---|---|
| Alcohol consumption | |||
| All women | |||
| Abstainers | 660/529 | 1.00b | |
| Ex-drinkers | 15/10 | 1.34 (0.56–3.22) | 0.51 |
| Current drinkers | 334/470 | 0.63 (0.52–0.76) | <0.001 |
| Premenopausal women | |||
| Abstainers | 416/332 | 1.00b | |
| Ex-drinkers | 10/4 | 2.44 (0.71–8.39) | 0.16 |
| Current drinkers | 246/335 | 0.66 (0.53–0.84) | 0.001 |
| Postmenopausal women | |||
| Abstainers | 244/197 | 1.00b | |
| Ex-drinkers | 5/6 | 0.68 (0.17–2.67) | 0.58 |
| Current drinkers | 88/135 | 0.55 (0.38–0.78) | 0.001 |
| Type of alcohol consumed | |||
| All women | |||
| Abstainers | 660/529 | 1.00b | |
| Beer only | 82/103 | 0.65 (0.47–0.90) | 0.01 |
| Wine only | 37/91 | 0.40 (0.26–0.60) | <0.001 |
| Liquor only | 30/30 | 0.81 (0.47–1.39) | 0.44 |
| Premenopausal women | |||
| Abstainers | 416/332 | 1.00b | |
| Beer only | 70/81 | 0.73 (0.51–1.06) | 0.10 |
| Wine only | 19/60 | 0.30 (0.17–0.52) | <0.001 |
| Liquor only | 19/18 | 0.73 (0.37–1.47) | 0.38 |
| Postmenopausal women | |||
| Abstainers | 244/197 | 1.00b | |
| Beer only | 12/22 | 0.34 (0.15–0.75) | <0.01 |
| Wine only | 18/31 | 0.61 (0.32–1.16) | 0.13 |
| Liquor only | 11/12 | 0.88 (0.36–2.16) | 0.77 |
| Ethanol intake (g per day) | |||
| All women | |||
| None | 660/529 | 1.00b | |
| >0–<5 | 225/366 | 0.56 (0.45–0.69) | <0.001 |
| 5–<10 | 28/42 | 0.58 (0.35–0.98) | 0.04 |
| 10–<20 | 12/13 | 0.89 (0.39–2.03) | 0.78 |
| 20–<30 | 45/43 | 0.86 (0.54–1.37) | 0.53 |
| ⩾30 | 39/16 | 2.33 (1.26–4.31) | <0.01 |
| Premenopausal women | |||
| None | 416/332 | 1.00b | |
| >0–<5 | 175/265 | 0.62 (0.48–0.79) | <0.001 |
| 5–<10 | 20/27 | 0.62 (0.33–1.17) | 0.14 |
| 10–<20 | 8/9 | 0.85 (0.31–2.34) | 0.75 |
| 20–<30 | 32/29 | 0.86 (0.49–1.50) | 0.59 |
| ⩾30 | 21/9 | 2.28 (1.00–5.20) | 0.05 |
| Postmenopausal women | |||
| None | 244/197 | 1.00b | |
| >0–<5 | 50/101 | 0.41 (0.27–0.62) | <0.001 |
| 5–<10 | 8/15 | 0.49 (0.19–1.24) | 0.13 |
| 10–<20 | 4/4 | 0.97 (0.23–4.06) | 0.96 |
| 20–<30 | 13/14 | 0.97 (0.42–2.26) | 0.95 |
| ⩾30 | 18/7 | 2.29 (0.89–5.87) | 0.09 |
Abbreviations: CI=confidence interval; OR=odds ratio.
a
Estimates from unconditional logistic regression models included terms for age at interview (continuous), education (none, primary, secondary, tertiary), BMI (5-years ago), oral contraceptive use (never, ever), hormone replacement therapy (never, ever), breast cancer in first-degree relatives (no, yes), total energy intake (continuous), folate intake (continuous), tea drinking (no, yes) and menopausal status (no, yes; only for all women).
b
Reference category.