Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CUP Mut2 promotes deadenylation-dependent decapping. (A–C) A tethering assay with CUP Mut2 or GW182 was performed in control cells (treated with GST dsRNA and expressing GFP) and in cells depleted of DCP2 (DCP2 knockdown; KD) and expressing a catalytically inactive GFP-DCP2 mutant (E361Q). Samples were analyzed as described in Figure 1. The dashed line in A indicates the position of the deadenylated F-Luc-5BoxB mRNA.
