Table 1.

Role of Caveolin in cancer progression and metastasis

Authors	Year	Tumor entity	Main findings	Reference
Chen et al.	2011	lung	Increased Caveolin-1 expression indicated malignant progression and high invasion capability of NSCLC	[65]
Park et al.	2010	kidney	Caveolin-1 was upregulated in human renal cell carcinoma in comparison to adjacent tissue using cDNA microarray analysis	[27]
Li et al.	2010	lung	Caveolin-1 promoted lymph node metastasis in NSCLC	[26]
Rödel et al.	2009	rectum	Low Caveolin-1 expression in adenocarcinomas of the rectum was significantly related to better local control rates at 5 years and to an increased overall survival rate after preoperative chemoradiation	[64]
Hehlgans et al.	2009	pancreas	Caveolin-1 was overexpressed in pancreatic tumor cells compared to tumor stromal cells and pancreatic parenchymal cells	[47]
Tanase et al.	2009	pancreas	Caveolin-1 was overexpressed in ductal adenocarcinoma of the pancreas when compared to peritumoral tissue and associated with grade, stage and size of tumor	[59]
Ho et al.	2008	lung	Caveolin-1 expression was associated with a poor prognosis and with drug resistance in advanced NSCLC patients after Gemcitabine-based chemotherapy	[63]
Ando et al.	2007	esophagus	Caveolin-1 and -2 mRNA expression was significantly higher in esophageal squamous cell carcinoma than in corresponding normal esophageal mucosa	[61]
Barresi et al.	2006	brain (meningiomas)	Increased Caveolin-1 expression was correlated with worse patient survival and biological aggressiveness of meningiomas	[62]
Kato et al.	2002	esophagus	Caveolin-1 expression was correlated with a poor prognosis and lymph node metastasis in esophageal squamous cell carcinoma after surgery	[60]