Table I. This table shows the physiological and biochemical details of the 30 subjects32. We use muscle biopsies from a total of 30 subjects (10 subjects from each category). Data are means ± S.E. *Significantly different from the lean controls (p < 0.05), #significantly different from the lean and obese controls (p < 0.05).
| Control, lean | Control, obese | T2D | |
|---|---|---|---|
| n | 10 | 10 | 10 |
| Age (years) | 51 ± 1 | 49 ± 1 | 50 ± 1 |
| Weight (kg) | 71.6 ± 3.0 | 105.5 ± 6.4* | 102.2 ± 4.1* |
| BMI (kg/m2) | 24.2 ± 0.5 | 33.7 ± 1.4* | 33.5 ± 1.1* |
| Fasting plasma glucose (mm) | 5.7 ± 0.1 | 5.7 ± 0.2 | 10.0 ± 0.7# |
| Fasting serum insulin (pm) | 24.3 ± 5.7 | 52.7 ± 5.0* | 94.6 ± 10.1# |
| Glucose infusion rate (mg/min) | 383.3 ± 20.4 | 257.9 ± 28.3* | 117.8 ± 18.6# |
| HbA1c (%) | 5.5 ± 0.1 | 5.4 ± 0.1 | 7.7 ± 0.5# |
| Fasting total cholesterol (mm) | 5.29 ± 0.22 | 5.43 ± 0.41 | 5.42 ± 0.37 |
| Fasting LDL cholesterol (mm) | 2.94 ± 0.22 | 3.33 ± 0.33 | 3.20 ± 0.27 |
| Fasting HDL cholesterol (mm) | 1.85 ± 0.15 | 1.48 ± 0.15 | 1.36 ± 0.03* |
| Fasting plasma triglyceride (mm) | 1.12 ± 0.16 | 1.35 ± 0.18 | 1.93 ± 0.40 |