Table II. The 12 proteins found to be differentially abundant are listed in this table. The accession number for each protein is listed along with the number of unique peptides assigned to each protein. The overall protein ratios identified by iTRAQ are indicated for each protein. These values are based on the total peptide information obtained for the individual proteins. *2 were isoform-specific. **51 were only assigned to Myosin-3, most were isoform-specific. ***9 were only assigned to Myosin-8, 2 were isoform-specific.
Protein name | Acc. No. | Unique peptides | Average (Lean/T2D) | Std dev. (Lean/T2D) | Average (Obese/T2D) | Std dev. (Obese/T2D) |
---|---|---|---|---|---|---|
Adenosine deaminase | P00813 | 3 | 1.45 | 0.46 | 1.63 | 0.48 |
Alcohol dehydrogenase 1B | P00325 | 13 | 1.68 | 0.38 | 2.46 | 0.76 |
Apolipoprotein A-I | P02647 | 2 | 1.32 | 0.02 | 1.27 | 0.10 |
Eukaryotic initiation factor 4A-I | P60842 | 15 | 0.72 | 0.15 | 0.79 | 0.13 |
Fatty acid-binding protein | P05413 | 6 | 0.75 | 0.12 | 0.93 | 0.07 |
Heat shock protein beta-6 | O14558 | 7 | 1.31 | 0.23 | 1.54 | 0.28 |
Hemoglobin subunit alpha | P69905 | 5 | 1.55 | 0.47 | 1.26 | 0.19 |
Macrophage-capping protein | P40121 | 3 | 1.30 | 0.05 | 1.15 | 0.02 |
Myosin-2 | Q9UKX2 | 12* | 0.84 | 0.28 | 0.95 | 0.35 |
Myosin-3 | P11055 | 80** | 0.76 | 0.14 | 0.77 | 0.16 |
Myosin-8 | P13535 | 37*** | 0.76 | 0.13 | 0.72 | 0.15 |
Tenascin | P24821 | 13 | 0.78 | 0.18 | 0.60 | 0.21 |