FIGURE 4.

Effect of the lipolysis inhibitor niacin on GH-induced elevation of serum FGF21 in mice. Sera were collected at different time points after GH treatment (1.5 mg/kg body weight) in the presence or absence of niacin (100 mg/kg body weight) as shown in (A) and then subjected to the analysis for FFA (B) and FGF21 levels (C) by using FFA Half Micro Test and ELISA, respectively. **, p < 0.01 versus niacin+GH group at the same time point, and #, p < 0.05; ##, p < 0.01 versus PBS+GH group at 0 h, respectively (n = 6).