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Two-dimensional class averages of intact αIIbβ3. Representative class averages of DDM-solubilized αIIbβ3 in Ca2+/Mg2+(A and B), Mn2+/Ca2+(C–E), and Mn2+/Ca2+ with L-739758 (F–H) are shown. The percentage of the particles represented by bent (A, C, and F), extended-closed (B, D, and G), and extended-open (E and H) is shown below the panels.
