Figure 2. Orientation specific homopolymer histograms.

Mean residual ionic current (gray) and fitted Gaussian curves are shown for homopolymer adenine (‘poly-dA’, black), cytosine (‘poly-dC’, red), thymine (‘poly-dT’, green), and guanine (‘poly₃-dG’, blue) for (A) 3′ threading and (B) 5′ threading. With 3′ threading, poly-dA and poly₃-dG overlap by 27% of the area of the two Gaussians. With 5′ threading, poly-dA and poly₃-dG overlap by 2% and poly-dC and poly-dA overlap by 0.1% of the area of the two Gaussians.