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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Gastroenterology. 2011 Jun 23;141(4):1393–1403.e5. doi: 10.1053/j.gastro.2011.06.040

Figure 3. Effect of diet and genotype on hepatic expression of nuclear regulators involved in cholesterol homeostasis.

Figure 3

(A) Sterol-response element binding protein-2 (SREBP-2), (B) liver-receptor homolog-1 (LRH-1), (C) farnesoid X-receptor (FXR), and (D) small heterodimer partner (Shp) expression at 12-(□) and 24- (▪) weeks was assessed using western blotting of isolated hepatic nuclear protein. TATA-box binding protein (TBP) (shown in panel B) was used as a loading control. Same mice as preceding figures. *P<0.05, vs. diet-matched control. #P<0.05, vs. genotype-matched control. †P<0.05, vs. time-matched control.