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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Gastroenterology. 2011 Jun 23;141(4):1393–1403.e5. doi: 10.1053/j.gastro.2011.06.040

Figure 5. Dietary cholesterol modulates hepatic cholesterol content and liver injury, but not other lipid profiles in NASH.

Figure 5

(A) Serum alanine transaminase (ALT), (B) total hepatic cholesteryl ester (CE), and (C) hepatic free cholesterol (FC) content in WT (□) and foz/foz (▪) mice (n values as per METHODS) fed HF-diet containing 0, 0.2 or 2.0% (w/w) cholesterol for 24-weeks. (D) Hepatic TG, (E) diacylglycerides (DAG), and (F) total free fatty acids (FFA), as determined by HPLC. *P<0.05, vs. diet-matched control. #P<0.05, vs. genotype-matched, 0.0% cholesterol groups. †P<0.05, vs. genotype-matched, 0.2% cholesterol groups