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Marizomib (NPI-0052) and P2 analog structures.
 | |||
|---|---|---|---|
| NPI-# | P2 | Structural Class | MWt |
| Marizomib (NPI-0052) | CH2CH2Cl | LG | 313.78 |
| NPI-2056a | CH2CH2Cl | LG | 315.80 |
| NPI-2053 | CH2CH2Br | LG | 358.23 |
| NPI-2070 | CH2CH2I | LG | 405.24 |
| NPI-2151 | CH2CH2OTosyl | LG | 449.53 |
| NPI-2104 | CH2CH2SCN | Non-LG | 336.41 |
| NPI-2078 | CH2CH2N3 | Non-LG | 320.35 |
| NPI-2077 | CH2CH2OH | Non-LG | 295.34 |
| NPI-0047 | CH2CH3 | Non-LG | 279.34 |
Cyclohexenyl is replaced with cyclohexyl in NPI-2056 only.
