Table 5.
Genes identified as regulated at both 10 and 30 min in response to ApoEdpL-Wd
| Gene name and regulation status | Name | Regulation at: |
myo5Δ/Δ expression ratioc | Description | |
|---|---|---|---|---|---|
| 10 mina | 30 minb | ||||
| Upregulated | |||||
| orf19.675 | 11.970 | 2.745 | 23.279 | Similar to cell wall proteins | |
| orf19.2959.1 | 6.862 | 3.214 | 10.169 | ORF predicted by annotation working group | |
| orf19.6659 | GAP6 | 6.470 | 28.310 | 0.909 | Putative general amino acid permease |
| orf19.4082 | DDR48 | 5.568 | 1.897 | 31.251 | Immunogenic stress-associated protein |
| orf19.6937 | PTR2 | 5.199 | 12.830 | 0.729 | Putative oligopeptide transporter |
| orf19.24 | RTA2 | 4.543 | 2.230 | 17.373 | Putative floppase |
| orf19.97 | CAN1 | 3.209 | 4.484 | 0.980 | Amino acid permease, transports basic amino acids |
| orf19.6877 | 3.107 | 2.181 | 4.479 | Predicted ORF in assemblies 19, 20, and 21 | |
| orf19.1193 | GNP1 | 2.762 | 9.543 | 1.242 | Protein described as similar to asparagine and glutamine permease |
| orf19.2125 | 2.534 | 2.146 | 13.254 | Predicted ORF in assemblies 19, 20, and 21 | |
| orf19.4940 | 2.188 | 5.554 | 0.964 | Putative histidine permease | |
| orf19.4304 | GAP1 | 2.084 | 5.618 | 0.796 | General amino acid permease |
| orf19.3548.1 | WH11 | 2.020 | 1.886 | 17.890 | Cytoplasmic protein expressed specifically in white-phase yeast-form cells |
| orf19.986 | GLY1 | 1.686 | 2.365 | 1.129 | L-Threonine aldolase |
| orf19.1353 | 1.659 | 3.013 | 0.806 | Predicted ORF in assemblies 19, 20, and 21 | |
| Downregulated | |||||
| orf19.6844 | ICL1 | 0.663 | 0.442 | 1.766 | Isocitrate lyase |
| orf19.541 | 0.536 | 0.591 | 0.814 | Predicted ORF in assemblies 19, 20, and 21 | |
| orf19.2693 | 0.503 | 0.622 | 1.572 | Increased transcription is observed upon benomyl treatment | |
| orf19.4063 | GPT1 | 0.365 | 0.458 | 1.134 | GABA/polyamine transporter |
| orf19.1608 | 0.300 | 0.304 | 1.033 | Predicted ORF in assemblies 19, 20, and 21 | |
a
Fold expression change for cells exposed to subinhibitory concentrations of ApoEdpL-W after 10 min versus unexposed cells.
b
Fold expression change for cells exposed to subinhibitory concentrations of ApoEdpL-W after 30 min versus unexposed cells.
c
Fold expression change of the myo5Δ/Δ mutant to the wild type.
d
Only genes regulated by a factor of 1.5 with a P value of <0.05 have been considered.