Fig. 4.

Genes of the ergosterol pathway upregulated in the presence of EMC120B12. All transcripts identified to be upregulated in the presence of EMC120B12 in the schematic representation of the ergosterol pathway of C. albicans are shown in dark gray. In addition, the transcript levels of one of the major regulators of the ergosterol (ERG) pathway, UPC2, were identified as upregulated as well. A-CoA, acetyl coenzyme A; HMG-CoA, 3-hydroxy-3-methyl-glutaryl coenzyme A; IPP, Δ³-isopentenyl pyrophosphate; DMAPP, dimethylallyl pyrophosphate.