Fig. 1.
Schematic representation of the genetic environment of the blaOXA-198 gene. The 5′ conserved segment (5′-CS) contains the integrase gene intI1, while the 3′-CS contains the qacEΔ1, sul1, and orf5 genes typical of class I integrons. Filled circles indicate attC sites. Arrows indicate the direction of transcription of the coding regions. IRi of the Tn6060-like sequence is shown. paeR7IM and paeR7IN code for an adenine-specific methyltransferase and a DNA invertase, respectively. Genes tniB and tniA, involved in transposition, are located downstream of orf5.