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Cytotoxicity of DB1127, mefloquine, and mefloquine (+)- and (−)-enantiomers against human foreskin fibroblasts (A) and rat hepatoma cells (B). Cells were grown to confluence and incubated with different concentrations of the drugs for 72 h. Assessments were made by measuring fluorescence in a resazurin cell viability assay. Values are presented as percentages relative to the values for controls without the compound.
