Table 1.

Laboratory and clinical data for 13 volunteers challenged with groundwater seeded with 8FIIb NV inoculum

Storage time of groundwater (days)	No. infected/no. challenged	Seroconversion	Duration (range of days postchallenge) of:
			Viral sheddinga	Clinical symptomsb
0	2/2	Yes/yes	NDc/2–13	2–4/2–2
7	2/2	Yes/yes	2–15/5–13	1–4/2–3
14	2/2	Yes/yes	2–22/2–22	2–3/2–3
21	1/4	No/no/yesd/no	ND/ND/2–13/ND	NAe/NA/2–3/NA
27	1/1	Yes	2–34	2–3
61	2/2	Yes/yes	3–22/4–4	2–3/3–5

^aViral shedding was defined as the presence of NV RNA, detected by RT-PCR, in any postchallenge stool sample.

^bClinical symptoms included diarrhea (≥2 unformed stools/day), fever (>38°C), and vomiting and self-reported nausea, abdominal cramping, headache, myalgia, and fatigue.

^cND, not detected.

^dCorresponds to the 1 infected volunteer at 21 days of stored water.

^eNA, not applicable.