Comparison of S. Typhimurium genes expressed in the lumens of newly hatched chicks with those expressed in in vitro-grown bacteria, classified according to COGs. Black bars, cecal contents; white bars, in vitro. The classified genes were found to be significantly different, with a >2-fold change in expression and a P value of less than 0.05. COGs classification abbreviations: C, energy production and conversion; D, cell cycle control, mitosis, and meiosis; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; G, carbohydrate transport and metabolism; H, coenzyme transport and metabolism; I, lipid transport and metabolism; J, translation; K, transcription; L, replication, recombination, and repair; M, cell wall/membrane biogenesis; N, cell motility; O, posttranslational modification, protein turnover, and chaperones; P, inorganic ion transport and metabolism; Q, secondary metabolites biosynthesis, transport, and catabolism; R, general function prediction only; S, function unknown; T, signal transduction mechanisms.