Table 4.

S. Typhimurium genes upregulated at the mucosal wall^a

COGs class	Locus tag	Gene	Function or product	Change in expression level (fold)	P value
Amino acid transport and metabolism	STM3592	yhiP	Putative peptide transport protein	2.08	0.049
Carbohydrate transport and metabolism	STM0310	gmhA	Phosphoheptose isomerase	2.06	0.037
	STM1558		Putative glycosyl hydrolase	2.13	0.017
	STM2431	ptsH	Phosphohistidinoprotein-hexose phosphotransferase	2.29	0.017
	STM2433	crr	Glucose-specific IIA component	2.4	0.036
Cell cycle control, mitosis, and meiosis	STM0132	ftsA	ATP-binding cell division protein	2.37	0.019
	STM3371	yhdE	Putative inhibitor of septum formation	2.26	0.0198
	STM3374	mreB	Rod shape-determining protein	2.13	0.014
Cell motility	STM1177	flgE	Flagellar hook protein	2.64	0.03
Cell wall/membrane biogenesis	STM0124	murF	d-Alanine-d-alanine ligase	2.09	0.044
Energy production and conversion	STM4439	cybC	Cytochrome b562	2.06	0.03
Function unknown	STM0119	yabB	Putative cytoplasmic protein	2.28	0.042
	STM1088	pipB	Secreted effector protein	2.35	0.016
	STM3347	yhcB	Putative periplasmic protein	2.42	0.037
General function prediction only	STM1581	yddE	Putative phenazine biosynthetic protein	2.02	0.045
	STM2580	era	GTPase	2.09	0.028
	STM2969	ygdH	Putative nucleotide binding	3.18	0.012
Inorganic ion transport and metabolism	STM4324	cutA	Putative periplasmic divalent cation tolerance protein	2.3	0.02
Not in COGs	STM0471	ylaC	Putative inner membrane protein	2.06	0.003
	STM1059	ycbW	Putative cytoplasmic protein	2.71	0.03
	STM1092		Putative cytoplasmic protein	2.32	0.024
	STM1601	ugtL	Putative membrane protein	2.1	0.04
	STM2983	orfX	Putative lipoprotein	2.09	0.01
Nucleotide transport and metabolism	STM1163	pyrC	Dihydroorotase	2.09	0.013
Posttranslational modification, protein turnover, and chaperones	STM1682	tpx	Thiol peroxidase	2.79	0.038
	STM3342	sspA	Stringent starvation protein A	2.23	0.041
Transcription	STM1704		Putative regulatory protein	2.73	0.022
	STM3320	rpoN	Sigma 54	2.09	0.022
	STM3515	yciT	Transcriptional activator	2	0.026
	STM4318		Putative acetyltransferase	2.198	0.019
Translation	STM3418	rpsM	30S ribosomal subunit protein S13	2.73	0.026

^aGenes selected as genes of interest showed a >2-fold increase and a P value of <0.05.