Table 5.

S. Typhimurium genes downregulated at the mucosal wall^a

COGs class	Locus tag	Gene name	Function or product	Change in level of expression (fold)	P value
Amino acid transport and metabolism	STM0067	carB	Carbamoyl-phosphate synthase large subunit; putative ABC transporter	2.9	0.035
	STM1255		Periplasmic binding protein	2.49	0.044
	STM2055	pduU	Polyhedral body protein	2.097	0.031
	STM1257		Putative ABC transporter protein	2.03	0.006
	STM3594	prlC	Oligopeptidase A	2.09	0.0496
Carbohydrate transport and metabolism	STM3784		Putative phosphotransferase system mannitol/fructose-specific IIA domain	2.32	0.0199
Cell wall/membrane biogenesis	STM2120	asmA	Suppressor of OmpF assembly mutants	2.12	0.049
Energy production and conversion	STM2057	pduW	Propionate kinase	2.1	0.006
	PSLT027	ccdA	Antidote	2.14	0.045
	STM0813	ybhP	Putative cytoplasmic protein	2.09	0.025
	STM2007		Tetratricopeptide repeat protein	2.33	0.034
Not in COGs	STM0903		Putative chaperone	2.79	0.003
	STM2041	pduD	Propanediol dehydratase medium subunit	2.58	0.04
	STM3688		Putative cytoplasmic protein	2.16	0.0499
Replication, recombination, and repair	STM4168	nfi	Endonuclease V	2.22	0.011
Transcription	STM3773		Putative transcriptional regulator	2.07	0.019
Translation	STM2665	yfiA	Ribosome stabilization factor	2.75	0.01

^aGenes selected as genes of interest showed a >2-fold change in expression levels and a P value of <0.05.