Table 1.
Mouse plasma lipid and free fatty acid measurementsa
Mouse diet and genotype | FFA (mM) | TG (mg/dl) | SM (mg/dl) | Chol (mg/dl) | PC (mg/dl) |
---|---|---|---|---|---|
Chow | |||||
WT | 0.9 ± 0.3 | 75 ± 13 | 22 ± 3 | 110 ± 15 | 112 ± 13 |
Sptlc2+/− | 0.5 ± 0.1* | 51 ± 10** | 19 ± 2 | 109 ± 36 | 118 ± 35 |
High fat | |||||
WT | 1.6 ± 0.2 | 109 ± 16 | 35 ± 2 | 190 ± 19 | 201 ± 21 |
Sptlc2+/− | 1.2 ± 0.1** | 81 ± 12* | 28 ± 2* | 198 ± 11 | 198 ± 25 |
Values are means ± SD (n = 10). *,P < 0.05; **, P < 0.01 compared to WT. FFA, free fatty acids; TG, triglycerol; Chol, cholesterol.