Table 3.
Comparison of sensitivity and specificity data between different commercial and in-house assays
| Assaya | No. of laboratories using the indicated assay | EV detection |
EV71 detection |
CA16 detection |
|||
|---|---|---|---|---|---|---|---|
| No. of correct positive results/total no. of positive results (% sensitivity) | No. of correct negative results/total no. of negative results (% specificity) | No. of correct postivie results/total no. of postive results (% sensitivity) | No. of correct negative results/total no. of negative results (% specificity) | No. of correct positive results/total no. of postive results (% sensitivity) | No. of correct negative results/total no. of negative results (% specificity) | ||
| A | 17 | 265/272 (97.4) | 65/68 (95.6) | 114/153 (74.5)b | 181/187 (96.8) | 146/153 (95.4) | 185/187 (98.9) |
| B | 12 | 191/192 (99.5) | 48/48 (100) | 106/108 (98.1) | 131/132 (99.2) | 106/108 (98.1) | 132/132 (100) |
| C | 3 | 44/48 (91.7) | 10/12 (83.3) | 24/27 (88.9) | 33/33 (100) | 25/27 (92.6) | 33/33 (100) |
| D | 2 | 28/32 (87.5)b | 7/8 (87.5) | 0/18 (0)b | 22/22 (100) | 14/18 (77.8) | 21/22 (95.5) |
| E | 1 | 15/16 (93.8) | 4/4 (100) | 7/9 (77.8) | 11/11 (100) | 9/9 (100) | 11/11 (100) |
| F | 1 | 16/16 (100) | 4/4 (100) | 8/9 (88.9) | 11/11 (100) | 9/9 (100) | 11/11 (100) |
| In-house | 5 | 80/80 (100) | 19/20 (95) | 44/45 (97.8) | 53/55 (96.4) | 42/45 (93.3) | 55/55 (100) |
| Total | 41 | 639/656 (97.4) | 157/164 (95.7) | 303/369 (82.1) | 442/451 (98) | 351/369 (95.1) | 448/451 (99.3) |