Table 3.
Genes upregulated by rspa
| Open reading frame category and name | Fold change | Gene | Description |
|---|---|---|---|
| Secreted proteins | |||
| MW1755 | 6.7 | splA | Serine protease SplA |
| MW1754 | 9.0 | splB | Serine protease SplB |
| MW1753 | 6.0 | splC | Serine protease SplC |
| MW1752 | 6.0 | splF | Serine protease SplD, putative |
| MW1850 | 5.4 | scpA | Cysteine protease precursor SspB |
| MW1767 | 2.9 | lukD | Leukotoxin |
| MW1940 | 2.8 | hlb | Phospholipase C |
| MW0297 | 2.0 | geh | Glycerol ester hydrolase |
| MW0345 | 2.3 | Staphylococcal enterotoxin, putative | |
| MW0767 | 2.8 | empBP | Secretory extracellular matrix and plasma binding protein |
| MW1880 | 2.5 | map | Map protein, authentic frameshift |
| Regulation | |||
| MW2002 | 2.0 | kdpD | Sensor histidine kinase KdpD |
| MW2003 | 2.3 | kdpE | DNA binding response regulator KdpE |
| Metabolism | |||
| MW1675 | 2.7 | fhs | Formate-tetrahydrofolate ligase |
| MW0070 | 3.6 | plc | 1-Phosphatidylinositol phosphodiesterase |
| Other | |||
| MW2536 | 2.3 | nrdG | Anaerobic ribonucleoside triphosphate reductase activating protein |
| MW1609 | 2.6 | AbrB protein, putative | |
| MW0768 | 2.8 | Hypothetical protein | |
| MW0758 | 2.6 | Hypothetical protein | |
| MW0906 | 3.7 | Conserved hypothetical protein, similar to competence transcription factor | |
| COL-SA1713 | 2.9 | Hypothetical protein | |
| MW1851 | 4.6 | Hypothetical protein |
a
Upregulation indicates an increased expression level in the wild type compared to the rsp deletion mutant.