Fig. 1.

Alignment of serogroup 11 cps genes involved in capsule synthesis. Regulatory genes wzg, wzh, wzd, and wze are not shown. Highlighted genes include putative O-acetyltransferase genes (gray fill) and the CDP-glycerol synthetase, gct (vertical lines), which contains a frameshift mutation in the ST 11F and ST 11B cps loci (horizontal lines). The transposable element IS1167 is represented with arrows with black fill. Regions that share greater than 99% homology between cps loci are highlighted with gray boxes. Dotted boxes show a divergent region which is the result of the replacement of wcwC with wcwR. The ST 11A and 11D cps loci are 99.9% homologous. The ST 11E cps locus differs from ST 11A due to a disruptive mutation to wcjE (white asterisk). The 11A and 11E cps sequences are according to reference 5. The 11F, 11B, 11C, and 11D sequences are according to reference 2.