Fig. 2.

Virus is transferred to donor-derived B cells during γHV68 latency. (A) Representative dot plots showing the purity of sorted donor and host populations after busulfan treatment and bone marrow reconstitution. Host mice were B6.SJL-Ptprc^aPepc^b/Boy (CD45.1⁺Thy1.2⁺); donor mice were C57BL/6 (CD45.2⁺Thy1.2⁺). (B) At the indicated times after reconstitution, spleens were harvested, sorted into donor and host B cell populations, and analyzed by real-time PCR to determine γHV68 ORF50 gene copy numbers (n = 3 to 12/group).