TABLE 2.

Selectivity of M119/gallein in blocking downstream effector interactions

Blocked by M119/gallein
PLC β2, β3	Bonacci et al., 2006; Mathews et al., 2008
pREX guanine nucleotide exchange factor	Zhao et al., 2007; Lehmann et al., 2008; Qin et al., 2009
PI3K γ	Bonacci et al., 2006; Lehmann et al., 2008
GRK2	Bonacci et al., 2006; Casey et al., 2010
Not blocked by M119/gallein
N-type Ca2+ channel	P. Kammermeier, unpublished observations
Inwardly rectifying K+-channel	P. Kammermeier, unpublished observations
ERK1/2	Bonacci et al., 2006
ACII, IV, VI	C. Dessauer and V. Watts, unpublished observations