Table 5.
Group differences of regional mean diffusivity in the tracts of interest
| Tracts | Mean diffusivity, mean (SD) |
Model | |||
|---|---|---|---|---|---|
| Healthy controls | Non-fluent variant | Semantic variant | Logopenic variant | ||
| Left SLF | 0.61 (0.03) | 0.69 (0.06)** | 0.65 (0.05) | 0.67 (0.06)* | ** |
| Right SLF | 0.62 (0.04) | 0.68 (0.05) | 0.63 (0.04) | 0.64 (0.03) | NS |
| Left arcuate fasciculus | 0.61 (0.03) | 0.70 (0.05)** | 0.70 (0.07)** | 0.68 (0.06)** | *** |
| Right arcuate fasciculus | 0.62 (0.03) | 0.66 (0.06) | 0.63 (0.03) | 0.64 (0.04) | NS |
| Left SLF-II | 0.61 (0.04) | 0.68 (0.05)* | 0.65 (0.05) | 0.67 (0.05)* | ** |
| Right SLF-II | 0.61 (0.03) | 0.66 (0.06) | 0.62 (0.03) | 0.63 (0.04) | * |
| Left SLF-III | 0.64 (0.03) | 0.70 (0.05)* | 0.68 (0.04) | 0.68 (0.04) | * |
| Right SLF-III | 0.62 (0.03) | 0.68 (0.05) | 0.64 (0.04) | 0.65 (0.02) | * |
| Left SLF temporoparietal | 0.65 (0.03) | 0.73 (0.08) | 0.78 (0.10)*** | 0.74 (0.09)** | *** |
| Right SLF temporoparietal | 0.66 (0.03) | 0.70 (0.05) | 0.67 (0.05) | 0.71 (0.07)* | * |
| Left inferior longitudinal fasciculus | 0.65 (0.02) | 0.69 (0.04) | 0.82 (0.09)***a,c | 0.71 (0.10) | *** |
| Right inferior longitudinal fasciculus | 0.65 (0.02) | 0.67 (0.06) | 0.71 (0.07)* | 0.67 (0.04) | * |
| Left anterior inferior longitudinal fasciculus | 0.68 (0.04) | 0.73 (0.07) | 0.97 (0.13)***a,c | 0.76 (0.13) | *** |
| Right anterior inferior longitudinal fasciculus | 0.66 (0.04) | 0.69 (0.06) | 0.79 (0.11)**,a | 0.69 (0.06) | ** |
| Left medial inferior longitudinal fasciculus | 0.61 (0.03) | 0. 66 (0.04) | 0.77 (0.09)***,a,c | 0.67 (0.09) | *** |
| Right medial inferior longitudinal fasciculus | 0.63 (0.03) | 0.66 (0.07) | 0.68 (0.08) | 0.64 (0.06) | NS |
| Left posterior inferior longitudinal fasciculus | 0.67 (0.04) | 0.68 (0.03) | 0.72 (0.06) | 0.69 (0.04) | NS |
| Right posterior inferior longitudinal fasciculus | 0.65 (0.05) | 0.66 (0.04) | 0.67 (0.04) | 0.67 (0.05) | NS |
| Left uncinate fasciculus | 0.72 (0.03) | 0.76 (0.05) | 1.02 (0.19)***,a,c | 0.77 (0.07) | *** |
| Right uncinate fasciculus | 0.70 (0.03) | 0.73 (0.05) | 0.81 (0.09)***a,c | 0.72 (0.05) | *** |
Asterisks denote significantly impaired (or different) relative to healthy controls at *P < 0.05; **P < 0.01; ***P < 0.001. Superscript letters denote significantly different relative to the anon-fluent, bsemantic and clogopenic variants at P < 0.05. Mean diffusivity values are measured in mm2/s × 10−3.
NS = not significant.