Table 6.
Group differences of regional axial diffusivity λ// in the tracts of interest
| Tracts | λ//, mean (SD) |
Model | |||
|---|---|---|---|---|---|
| Healthy controls | Non-fluent variant | Semantic variant | Logopenic variant | ||
| Left SLF | 0.89 (0.03) | 0.95 (0.06) | 0.92 (0.05) | 0.95 (0.05)* | * |
| Right SLF | 0.89 (0.03) | 0.94 (0.05) | 0.90 (0.04) | 0.91 (0.03) | NS |
| Left arcuate fasciculus | 0.89 (0.02) | 0.95 (0.05) | 0.96 (0.07)* | 0.95 (0.06)* | ** |
| Right arcuate fasciculus | 0.89 (0.04) | 0.94 (0.05) | 0.90 (0.03) | 0.91 (0.05) | NS |
| Left SLF-II | 0.88 (0.04) | 0.93 (0.05) | 0.91 (0.05) | 0.94 (0.05)** | ** |
| Right SLF-II | 0.87 (0.03) | 0.93 (0.05) | 0.89 (0.04) | 0.90 (0.03) | * |
| Left SLF-III | 0.89 (0.03) | 0.94 (0.05) | 0.93 (0.04) | 0.94 (0.04)* | * |
| Right SLF-III | 0.89 (0.03) | 0.93 (0.05) | 0.90 (0.04) | 0.92 (0.02) | NS |
| Left SLF temporoparietal | 0.90 (0.03) | 0.94 (0.08) | 1.00 (0.10)** | 0.97 (0.08)* | ** |
| Right SLF temporoparietal | 0.90 (0.04) | 0.95 (0.06) | 0.92 (0.05) | 0.96 (0.06)* | * |
| Left inferior longitudinal fasciculus | 0.90 (0.04) | 0.95 (0.04) | 1.1 (0.07)***,a,c | 0.98 (0.09)* | *** |
| Right inferior longitudinal fasciculus | 0.88 (0.04) | 0.90 (0.05) | 0.95 (0.08)* | 0.91 (0.05) | * |
| Left anterior inferior longitudinal fasciculus | 0.86 (0.05) | 0.92 (0.07) | 1.13 (0.12)***,a,c | 0.95 (0.14) | *** |
| Right anterior inferior longitudinal fasciculus | 0.85 (0.04) | 0.87 (0.06) | 0.97 (0.12)**,a | 0.88 (0.06) | ** |
| Left medial inferior longitudinal fasciculus | 0.83 (0.04) | 0.87 (0.05) | 0.99 (0.09)***,a | 0.91 (0.10)* | *** |
| Right medial inferior longitudinal fasciculus | 0.83 (0.04) | 0.85 (0.08) | 0.89 (0.08) | 0.84 (0.06) | NS |
| Left posterior inferior longitudinal fasciculus | 1.00 (0.06) | 1.01 (0.04) | 1.08 (0.07) | 1.04 (0.07) | * |
| Right posterior inferior longitudinal fasciculus | 0.97 (0.07) | 0.96 (0.04) | 0.99 (0.08) | 1.00 (0.05) | NS |
| Left uncinate fasciculus | 0.96 (0.03) | 0.99 (0.05) | 1.24 (0.17)***,a,c | 1.01 (0.07) | *** |
| Right uncinate fasciculus | 0.95 (0.03) | 0.98 (0.06) | 1.03 (0.08)** | 0.96 (0.05) | ** |
Asterisks denote significantly impaired (or different) relative to healthy controls at *P < 0.05; **P < 0.01; ***P < 0.001. Superscript letters denote significantly different relative to the anon-fluent, bsemantic and clogopenic variants at P < 0.05. Values are measured in mm2/s × 10−3.
NS = not significant.