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. 2011 Sep 7;90(4):625–629. doi: 10.1038/clpt.2011.185

Figure 2.

Figure 2

Frequency histograms of stable therapeutic warfarin doses in mg/week, stratified by VKORC1 −1639G>A genotype in 3,616 patients recruited by the International Warfarin Pharmacogenetics consortium (IWPC) who did not carry the CYP2C9*2 or *3 allele (i.e., coded as *1*1 for US Food and Drug Administration (FDA) table and algorithm dosing). the range of doses within each genotype group recommended on the FDA table is shown via the shaded rectangle. the range of doses predicted using the IWPc dosing algorithm in these 3,616 patients is shown by the solid lines.