Number of shared and unique genes in the genomes of the six Cyanothece strains. Each bar represents the total number of genes in a genome. Protein sequences of the individual Cyanothece strains were compared with each other in order to identify the distribution of orthologs among different strains (see Materials and Methods). The number of genes in each genome having orthologs in one or more of the remaining five strains was determined and grouped accordingly. These gene groups are colored as follows: light blue, genes shared by all six genomes; grey, shared by 5 of the 6 genomes; dark blue, shared by 4 genomes; yellow, shared by 3 genomes; green, shared by two genomes;: red, genes unique to each Cyanothece strain. Orthologous sequences for about 1,700 genes are found in all genomes. Cyanothece 7425 has the highest number of unique genes, whereas Cyanothece 8801 and 8802 have the least, with most genes being shared between the two.