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. 2001 Apr 3;98(8):4575–4580. doi: 10.1073/pnas.071055798

Figure 4.

Figure 4

LOH analysis using microsatellite markers on the chromosome 10q21 locus. (A) LOH analysis by microcapillary electrophoresis and data analysis with the Applied Biosystems 310 genetic analyzer in representative samples. LOH was scored by comparing the peak heights of tumor DNA and matched normal DNA. (B) Tumor and normal tissue DNA were prepared from 20 patients and analyzed for LOH as described in Materials and Methods. Arrows indicate alleles showing loss. Tumor of patient 17 shows homozygous deletion with AFM220xe5. No such loss was noted when the same sample was coamplified with another microsatellite marker AFM063xc5.