Table 1.

Summary of LOH/homozygous deletion data for four loci mapped to chromosome 10q21 in clinically localized CaP

Patient	β-Actin	Markers
		AFMa299ya5	AFM220xe5	AFM 063xc5	AFM200wf4
1	ok	Normal	Normal	ND	ND
2	ok	Normal	Normal	Normal	R
3	ok	Normal	NI	NI	NI
4	ok	Normal	NI	Normal	NI
5	ok	Normal	Normal	Normal	Normal
6	ok	Normal	NI	ND	ND
7	ok	NI	NI	NI	LOH
8	ok	NI	NI	Normal	Normal
9	ok	NI	LOH	NI	NI
10	ok	Normal	LOH	Normal	Normal
11	ok	Normal	Normal	Normal	Normal
12	ok	NI	Normal	Normal	NI
13	ok	NI	NI	NI	NI
14	ok	Normal	Normal	Normal	LOH
15	ok	NI	LOH	LOH	Normal
16	ok	Normal	LOH	NI	Normal
17	ok	Normal	Homozygous deletion	Normal	Normal
18	ok	Normal	R	Normal	Normal
Number of informative cases		12/18	11/16	11/16	10/15
Number of LOH		0/12	5/11	1/11	2/10

Matching samples from 20 patients containing normal and tumor specimens were analyzed by four different microsatellite markers located on chromosome 10q21 encompassing ANX7 locus. Samples from 1–16 were derived from patients with primary prostate cancers. Samples 17 and 18 were from metastatic tumor patients. Only cases demonstrating LOH are illustrated. NI, non-informative; ND, not detected; R, to be repeated. β-actin was used for ascertaining similar amounts of input DNA. The microsatellite marker that is closest to ANX7 is AFM220xe5.