Improvement in various health-related quality of life measures with certolizumab pegol in PRECiSE 2. PCS, physical component summary; MCS, mental component summary; VAS, visual analog scale; IBDQ, inflammatory bowel disease questionnaire. *p < 0.05 (logistic regression). †p < 0.001 (logistic regression). Error bars represent the 95% confidence interval. Reprinted with permission from Macmillan Publishers Ltd [Feagan et al. 2009b, 104(8)], copyright © 2009.