. Author manuscript; available in PMC: 2011 Oct 5.

Published in final edited form as: Clin Cancer Res. 2009 Feb 1;15(3):1105–1111. doi: 10.1158/1078-0432.CCR-08-1743

Table 3.

Multivariate association of prostate cancer risk with each of the SNPs and family history

	Chr	Position^*	model	OR^*	95%CI	P^*
Family history				2.19	1.80–2.67	6.5E-15
Age				1.02	1.00–1.03	6.8E-03
Genographic region				0.46	0.38–0.54	1.7E-19
rs2660753	3p12	87,193,364	additive	1.32	1.12–1.55	8.0E-04
rs9364554	6q25	160,804,075	additive	1.08	0.98–1.19	0.11
rs10486567	7p15	27,749,803	dominant	1.39	1.04–1.85	0.03
rs6465657	7q21	97,654,263	additive	1.14	1.04–1.25	4.1E-03
rs16901979	8q24 (2)	128,194,098	additive	1.65	1.32–2.08	1.6E-05
rs6983267	8q24 (3)	128,482,487	additive	1.22	1.12–1.34	1.3E-05
rs1447295	8q24 (1)	128,554,220	dominant	1.16	1.01–1.34	0.04
rs1571801	9q33	121,506,927	additive	1.15	1.04–1.27	0.01
rs10993994^A	10q11	51,219,502	additive	1.16	1.06–1.27	1.8E-03
rs10896449^B	11q13	68,751,243	additive	1.12	1.02–1.22	0.02
rs4430796	17q12	33,172,153	additive	1.22	1.11–1.33	3.7E-05
rs1859962	17q24.3	66,620,348	additive	1.17	1.07–1.28	9.0E-04
rs5945619^C	Xp11	51,074,708	dominant	1.19	1.05–1.36	8.7E-03

Build35

rs79201517 (51,202,627) is in strong LD with rs10993994, r²=0.76)

rs7931342 (68,751,073) is in strong LD with rs10896449, r²=0.95)

rs5945572 (51,062,719) is in strong LD with rs5945619, r²=0.91)

OR* and P* are based on tests assuming an additive model, ajusting for age, geographic region and family history