Table 1. Combination indices for H342 and H258 treatment for 24 h, as computed by CalcuSyn for H2373 cells.
H342 (µM) | Fa | H258 (µM) | Fa | H342+H258 (Fa) | CI |
4.5 | 0.0133 | 18 | 0.0054 | 0.0329 | 1.186 |
9 | 0.3218 | 36 | 0.0231 | 0.1735 | 1.416 |
13.5 | 0.8759 | 72 | 0.0391 | 0.2392 | 1.918 |
18 | 0.9342 | 108 | 0.1133 | 0.3050 | 2.356 |
Note: CI (combination indices)>1 indicates antagoniusm; Fa, fraction affected.