Skip to main content
. 2011 Oct 5;6(10):e25973. doi: 10.1371/journal.pone.0025973

Figure 3. Depletion of Set1/MLL subunits by RNAi leads to reduction in H3K4me3 levels.

Figure 3

H3K4me3 (green) and DPY-27 (red) IF in control RNAi and Set1/MLL depletion animals shows a reduced H3K4me3 signal upon Set1/MLL RNAi in adult intestinal nuclei. Note that only DPY-30 depletion leads to a diffuse DCC localization phenotype. In all panels DAPI is shown in grayscale and scale bar equals 5 µm.