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. 2011 Oct 5;6(10):e25948. doi: 10.1371/journal.pone.0025948

Table 2. Demographic data of ALS patients with no bulbar signs at the time of testing (i.e. non-bulbar), with bulbar signs at the time of testing (i.e. bulbar) and healthy controls, and relative performance on the background neuropsychological tests.

Non-bulbar Bulbar Healthy controls F or Kruskal-Wallis H
(n 9) (n 6) (n 21)
Age in years 62.22 (17.64) 54.33 (18.02) 57.48 (12.91) NS
Gender (M:F) 7∶2 4∶2 14∶7 -
Education in years 13.67 (3.20) 16.83 (3.96) 17.02 (4.15) NS
Verbal Fluency: letters P, R, W 40.22 (11.33) 38.50 (18.64) 52.33 (10.87) 4.646*
Verbal Fluency: Index 3.83 (1.27) 5.17 (2.38) 2.85 (0.52) 7.898** §
Verbal Fluency: Category 18.33 (6.60) 19.50 (4.18) 22.05 (4.10) NS
GNT (0–30) 21.44 (4.07) 22.50 (2.17) 26.10 (2.43) 9.680**
VOSP: “Object Decision” (0–20) 17.44 (1.81) 18.83 (0.75) 18.29 (1.76) NS
VOSP: “Position Discrimination” (0–20) 20.00 (0.00) 19.83 (0.41) 19.81 (0.40) NS
VOSP: “Number Location” (0–10) 9.33 (0.71) 9.17 (1.17) 9.62 (0.97) NS
Hayling: “Overall” (1–10) 5.22 (1.20) 6.17 (1.17) 6.05 (1.20) NS
Hayling: “Sensible completion” (1–7) 5.33 (1.12) 6.00 (0.89) 6.05 (0.50) NS
Hayling: “Unconnected completion” (1–8) 5.11 (1.45) 6.00 (1.10) 5.76 (0.89) NS
Hayling: Errors (1–8) 5.89 (1.69) 6.50 (0.84) 6.33 (1.83) NS
Brixton (1–10) 5.89 (1.90) 8.33 (1.37) 7.10 (1.84) NS

GNT Graded Naming Test; NS not significant; SD standard deviation; VOSP Visual Object and Space Perception battery.

*p<0.05.

**p<0.001.

§

Bulbar patients significantly different from healthy controls.

Bulbar and non-bulbar patients significantly different from healthy controls.