Table 1.

Baseline Hemodynamics in Sham and CHF Rabbits before and after Ang-(1–7) Infusion

Variable	Sham+aCSF	Sham+Ang-(1–7)	CHF+aCSF	CHF+Ang-(1–7)	CHF+Ang-(1–7)+A779
N	13	11	11	10	3
Body Weight, kg	3.6±0.1	3.6±0.1	3.7±0.1	3.6±0.1	3.5±0.1
Heart Rate, bpm	198.5±4.6	186.8±4.5	248.0±5.5*	209.6±4.9†	221.5±5.5*†
MAP, mmHg	74.3±1.9	69.1±3.1	73.4±3.0	67.3±3.2	76.1±6.3
LVEDD, mm	16.2±0.5	16.3±0.4	17.1±0.4	16.6±0.6	16.7±0.1
LVSD, mm	7.1±1.4	7.5±0.3	13.6±0.4*	13.5±0.5*	13.8±0.2*
LVd Vol, ml	7.6±0.6	6.7±0.5	8.6±0.5	8.2±0.7	8.1±0.1
LVs Vol, ml	2.2±0.2	2.4±0.3	4.7±0.3*	4.8±0.5*	4.8±0.2*
FS %	34.2±1.7	35.9±0.8	20.5±0.5*	19.0±0.9*	18.0±1.0*
EF %	70.3±0.6	73.2±1.0	45.1±1.0*	42.3±1.7*	40.4±1.9*

Values are mean±SEM. LV indicates left ventricle; MAP, mean arterial pressure; LVEDD, left ventricular end-diastolic diameter; LVSD, left ventricular systolic diameter; LVd Vol, left ventricular diastolic diameter; LVs Vol, left ventricular systolic diameter; FS, fractional shortening; EF, ejection fraction

^*P<0.05 vs. Sham+aCSF,

^†P<0.05 vs. CHF+aCSF.