Table 1.
Toxicity screening of Imm-H against cultured cell lines
Cell line | Tissue origin* | IC50, μM |
---|---|---|
A2780 | Ovarian cancer | >150 |
OVCAR-3 | Ovarian cancer | >150 |
MCF-7 | Breast cancer | >150 |
SKBR3 | Breast cancer | >150 |
LNCAP | Prostate cancer | >150 |
PC3 | Prostate cancer | >150 |
HCT116 | Colon cancer | >150 |
LS174t | Colon cancer | >150 |
MIP | Colon cancer | >150 |
CACO-2 | Colon cancer | >150 |
A549 | Lung cancer | >150 |
LX-1 | Lung cancer | >150 |
HL60 | Leukemia | >150 |
HS27 | Fibroblast | >150 |
ABAE | Aortic endothelium† | 142 |
M109 | Lung cancer‡ | 60 |
MLF | Lung fibroblast‡ | 92 |
All cell lines are human unless otherwise specified.
Bovine cell line.
Murine cell line. Cells were cultured with Imm-H concentrations to 50 μM. No effect was scored as IC50 >150 μM.