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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Ann N Y Acad Sci. 2011 Sep;1233(1):320–326. doi: 10.1111/j.1749-6632.2011.06118.x

Figure 1.

Figure 1

This is an illustration of the effects of gabapentin and memantine on horizontal APN in one patient with multiple sclerosis (MS). (A–C) Binocular eye positions are plotted against time. Red traces represent the right eye and grey traces the left. The patient has a binocular jerk nystagmus with a superimposed monocular pendular nystagmus in the right eye. The amplitude of both forms of nystagmus is reduced during treatment with gabapentin (B) and memantine (C). Corresponding power spectra are plotted in D–F. The power spectrum of the pendular component is very sharp (D, red trace). The power spectrum of the jerk nystagmus is broader and lower (D, gray trace). Note that both gabapentin and memantine reduce the oscillation amplitude, but do not significantly affect its frequency distribution.