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. 2011 Aug 18;54(19):6761–6770. doi: 10.1021/jm200640v

Figure 1.

Figure 1

(A) Structure of the BET probe (+)-JQ1.(18) (B) Structure of the BET probe I-BET.(19a) (C) Structure of dihydroquinazolinone-containing 3,5-dimethylisoxazole derivative 1. (D) The concept employed in the design of the 3,5-dimethylisoxazole-based bromodomain inhibitors.