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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Osteoarthritis Cartilage. 2011 Jul 23;19(10):1210–1218. doi: 10.1016/j.joca.2011.07.005

Figure 5. BCP co-culture performs similarly in chondrogenic media compared to culture in growth.

Figure 5

media (*, p<0.001 compared to hMSC; +, p <0.001 compared to TGFβ treated hMSC; ◆, p = 0.0038 compared to JC; x, p = 0.045 compared to hMSC). In chondrogenic media, BCP and JC pellets produce more proteoglycan compared to hMSC in the presence or absence of TGFβ as assessed by DMMB, N=8 (A), a result that is consistent with Aggrecan IHC N≥3 (B). JC pellets showed increased expression of chondrogenic genes relative to BCPs and hMSC+TGFβ pellets. hMSC+TGFβ pellets had greater expression of hypertrophic genes than BCP pellets N=5 (C). Error bars represent 95% confidence intervals.