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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Free Radic Biol Med. 2011 Aug 12;51(9):1749–1757. doi: 10.1016/j.freeradbiomed.2011.08.004

Figure 1. Luciferase Reporter Constructs Used to Generate Stable Cell Lines.

Figure 1

A 4.4 kB of the human GCLc promoter were used to generate a series of luciferase reporter constructs. The diagram of the vector containing the full length, fully functional promoter (number 5) shows the locations of several AP-1 sites and AREs 1-4 (numbered in descending order from 5′ to 3′). Vector number 4 represents the full length promoter with a single nucleotide mutation in ARE4, and vectors 1-3 represent 3 truncated versions of the full length promoter.