Table 1.
Characteristics of study participants by comparison group, the Tennessee Colorectal Polyp Study (TCPS), 2003–2010.
| Controls | Polyp groups |
|||
|---|---|---|---|---|
| Characteristic | (N = 3,764) | Adenomas (N = 1,881) |
HPP only (N = 662) |
P value1 |
| Study site (%) | <0.001 | |||
| Vanderbilt University | 75.4 | 64.5 | 61.5 | |
| Veterans Affairs | 24.6 | 35.5 | 38.5 | |
| Age [years, mean (SD)] | 56.8 (7.7) | 58.5 (7.3) | 56.7 (7.0) | <0.001 |
| Sex (female, %) | 45.1 | 27.8 | 33.5 | <0.001 |
| Indications for colonoscopy (%)2 | ||||
| Screening | 58.2 | 57.2 | 55.7 | |
| Other | 41.8 | 42.8 | 44.3 | |
| Educational attainment (%)2 | <0.001 | |||
| High school or less | 24.0 | 29.6 | 30.8 | |
| Some college | 28.3 | 28.1 | 29.8 | |
| College graduate | 20.8 | 21.5 | 20.3 | |
| Graduate or professional education | 26.9 | 20.8 | 19.1 | |
| Race (white, %) | 89.4 | 89.2 | 90.5 | 0.625 |
| Enrolled before colonoscopy (%) | 93.4 | 72.7 | 85.2 | <0.001 |
| Colorectal cancer family history (%)2 | 8.6 | 9.8 | 8.0 | 0.298 |
| Regular cigarette smoking (%)2 | 48.3 | 59.3 | 69.2 | <0.001 |
| Regular alcohol consumption (%)2 | 42.4 | 45.5 | 48.5 | 0.001 |
| Body mass index (kg/m2, mean)3 | 28.1 | 28.9 | 28.9 | <0.001 |
| Regularly exercised (%)2 | 57.9 | 52.0 | 53.3 | <0.001 |
| Regular NSAIDs use2 | 59.8 | 53.8 | 59.2 | 0.002 |
| Total energy intake (kcal/day, mean)2 | 2014.4 | 2084.8 | 2064.7 | <0.001 |
| Total folate intake (µg/day, mean)2 | 508.0 | 532.7 | 501.0 | 0.075 |
HPP: hyperplastic polyp
1
Derived from ANOVA for continuous variables and x2 test for categorical variables.
2
Standardized by age (40–49, 50–59, 60–64, and ≥65 years old) and sex distribution of all study participants.
3
Standardized by age distribution (40–49, 50–59, 60–64, and ≥65 years old) of all study participants.