Table 3.
Association of meat intake and polyp risk, the Tennessee Colorectal Polyp Study (TCPS), 2003–2010.
| Intake Amount (g/day) |
Controls (N=3,764) |
Any polyps (N=2,543) |
Patient groups |
||||
|---|---|---|---|---|---|---|---|
| Adenomas (N=1,881) |
HPP only (N=662) |
||||||
| (n) | n | OR (95% CI)1 | n | OR (95% CI)1 | n | OR (95% CI)1 | |
| All meat (g/day) | |||||||
| ≤59.0 | 977 | 545 | 1.0 (reference) | 427 | 1.0 (reference) | 118 | 1.0 (reference) |
| 59.1–90.9 | 929 | 496 | 1.0 (0.9–1.2) | 352 | 0.9 (0.8–1.1) | 144 | 1.3 (1.0–1.7) |
| 91.0–138.6 | 929 | 669 | 1.2 (1.0–1.4) | 484 | 1.1 (0.9–1.3) | 185 | 1.5 (1.1–1.9) |
| ≥138.7 | 929 | 833 | 1.3 (1.1–1.5) | 618 | 1.2 (1.0–1.4) | 215 | 1.5 (1.2–2.0) |
| P- trend | <0.001 | 0.013 | 0.002 | ||||
| Red meat (g/day)2 | |||||||
| ≤9.5 | 1118 | 540 | 1.0 (reference) | 398 | 1.0 (reference) | 142 | 1.0 (reference) |
| 9.6–28.4 | 932 | 581 | 1.2 (1.0–1.4) | 435 | 1.2 (1.0–1.5) | 146 | 1.1 (0.9–1.5) |
| 28.5–51.3 | 792 | 581 | 1.3 (1.1–1.5) | 428 | 1.2 (1.0–1.5) | 153 | 1.2 (0.9–1.6) |
| ≥51.4 | 922 | 841 | 1.4 (1.2–1.6) | 620 | 1.4 (1.2–1.6) | 221 | 1.3 (1.0–1.7) |
| P- trend | <0.001 | <0.001 | 0.029 | ||||
| Chicken (g/day) | |||||||
| ≤10.1 | 892 | 649 | 1.0 (reference) | 478 | 1.0 (reference) | 171 | 1.0 (reference) |
| 10.2–40.3 | 975 | 680 | 1.0 (0.9–1.2) | 515 | 1.1 (0.9–1.3) | 165 | 0.9 (0.7–1.2) |
| 40.4–50.0 | 1266 | 786 | 1.0 (0.9–1.2) | 571 | 1.0 (0.9–1.2) | 215 | 1.0 (0.8–1.2) |
| ≥50.1 | 631 | 428 | 1.0 (0.9–1.2) | 317 | 1.1 (0.9–1.3) | 111 | 1.0 (0.7–1.3) |
| P- trend | 0.809 | 0.812 | 0.962 | ||||
| Processed meat (g/day)3 | |||||||
| 0 | 1103 | 567 | 1.0 (reference) | 427 | 1.0 (reference) | 140 | 1.0 (reference) |
| 0.1–8.0 | 816 | 487 | 1.2 (1.0–1.4) | 356 | 1.1 (0.9–1.4) | 131 | 1.2 (0.9–1.6) |
| 8.1–22.4 | 924 | 622 | 1.2 (1.0–1.4) | 453 | 1.1 (0.9–1.3) | 169 | 1.2 (1.0–1.6) |
| >22.5 | 921 | 867 | 1.3 (1.1–1.5) | 645 | 1.3 (1.1–1.5) | 222 | 1.4 (1.1–1.8) |
| P- trend | 0.003 | 0.010 | 0.024 | ||||
| Red meat2 to chicken ratio | |||||||
| 0.25–0.67 | 1142 | 548 | 1.0 (reference) | 409 | 1.0 (reference) | 139 | 1.0 (reference) |
| 0.68–1.00 | 1267 | 779 | 1.1 (0.9–1.2) | 572 | 1.0 (0.9–1.2) | 207 | 1.2 (0.9–1.5) |
| 1.01–1.50 | 545 | 451 | 1.3 (1.0–1.5) | 331 | 1.3 (1.0–1.6) | 120 | 1.4 (1.0–1.8) |
| >1.51 | 810 | 765 | 1.3 (1.1–1.6) | 569 | 1.3 (1.1–1.6) | 196 | 1.4 (1.1–1.8) |
| P- trend | <0.001 | 0.001 | 0.010 | ||||
HPP: hyperplastic polyp.
1
Adjusted for age, sex, race, study sites, educational attainment, and indications for colonoscopy, smoking, alcohol consumption, BMI, physical activity, regular NSAIDs use, total energy intake, and recruitment before or after colonoscopy.
2
Includes hamburgers, cheeseburgers, beef patties/beef steaks, pork chops/ham steaks, and short ribs or spareribs.
3
Includes bacon, sausage, and hotdogs/franks.