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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: J Invest Dermatol. 2011 Jun 30;131(11):2306–2315. doi: 10.1038/jid.2011.188

Figure 2. Decreased FAK or Src expression in H-2Kd-Ecad-II-4 cells is associated with inhibition of tumor cell motility.

Figure 2

WB analysis of lysates of sh-FAK- and sh-Src-H-2Kd-Ecad-II-4 cells showed a decrease in FAK or Src levels, respectively, when compared to their levels in sh-Scrambled-H-2Kd-Ecad-II-4 cells (a). Scrape-wounded cultures of sh-Scrambled- (b, c), sh-FAK- (d, e) and sh-Src-H-2Kd-Ecad-II-4 cells (f, g), and of sh-Scrambled-II-4 cells (h, i) were imaged at 0 and 24hr following injury. Lines indicate the wound gaps. The mean ± SD of wound closure for each cell line are indicated and show the average change in the gaps at 24hr relative to time 0 (j). P values indicate significant changes in wound closure of sh-Scrambled-II-4, sh-FAK- and sh-Src-H-2Kd-Ecad-II-4 cells in comparison to sh-Scrambled-H-2Kd-Ecad-II-4 cells.