Skip to main content
. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: J Immunol. 2011 Jan 31;186(5):2792–2799. doi: 10.4049/jimmunol.1003353

FIGURE 5.

FIGURE 5

Differential role of HS5 for IL-4 expression in T-CD4 T cells. A, IL-4 production by T-CD4 T cells on Th1 and Th2 differentiation. Splenic CD4 T cells from BM chimera shown were differentiated as in Fig. 1A and analyzed for IL-4 and IFN-γ expression. B, Th2 differentiated cells from the same chimeras in A were analyzed to compare the expression of IL-4 and GFP. Cells from Δ5a Tg mice from each chimera are shown. Numbers indicate percentage of cells in each quadrant. Bar graphs are mean ± SD of three to four mice in each group. C, Δ5a originated CD4 T cells from [Δ5a+Tg→Aβ−/−] mice were differentiated to Th1 and Th2, and analyzed for IL-4 and GFP expression. Bar graphs (right panels) show each subpopulation in the dot plot.