Table 3.
Multivariate ordinal logistic regression analysis of risk factors associated with polyp size in males and females
| Males (n = 48,395) | Females (n = 34,246) | ||||
|---|---|---|---|---|---|
| OR | (95% CI) | OR | (95% CI) | ||
| Age | |||||
| < 50 | 1.00 | 1.00 | |||
| 50 - 59 | 1.06 | (0.98 - 1.16) | 1.00 | (0.91 - 1.11) | |
| 60 - 69 | 1.29 | (1.18 - 1.40)** | 1.14 | (1.03 - 1.26)* | |
| 70 - 79 | 1.36 | (1.24 - 1.49)** | 1.34 | (1.20 - 1.49)** | |
| 80+ | 1.55 | (1.35 - 1.79)** | 1.46 | (1.25 - 1.70)** | |
| Site | |||||
| Academic | 1.00 | 1.00 | |||
| Community/HMO | 1.26 | (1.18 - 1.34)** | 1.22 | (1.13 - 1.33)** | |
| VA/Military | 0.97 | (0.90 - 1.05) | 0.90 | (0.78 - 1.03) | |
| Race | |||||
| White | 1.00 | 1.00 | |||
| Black | 1.31 | (1.21 - 1.42)** | 1.36 | (1.24 - 1.48)** | |
| Location | |||||
| Distal Colon and rectum | 1.00 | 1.00 | |||
| Proximal Colon | 1.11 | (1.08-1.15)** | 1.33 | (1.27-1.39)** | |
| Number of polyps | |||||
| Single | 1.00 | 1.00 | |||
| Multiple | 3.41 | (3.29 - 3.54)** | 3.04 | (2.90 - 3.18)** | |
| Family history | |||||
| Negative | 1.00 | 1.00 | |||
| Positive | 1.00 | (0.95 - 1.05) | 1.03 | (0.98 - 1.08) | |
All odds ratios are adjusted for all other covariates in the table. * P < .01 **P < .0001
Odds Ratios (OR) and 95% Confidence Intervals (CI) obtained from ordinal logistic regression. Polyp size was stratified into 4 categories: 0-5, > 5-9, > 9-15, and > 15-40 mm. The odds ratio is the risk associated with an increase of polyp size corresponding to moving from one category to the next larger category, i.e. ≤ 5 mm vs. > 5 mm; ≤ 9 vs. > 9; ≤ 15 vs. > 15 mm.