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. 2011 Oct 6;6(10):e24832. doi: 10.1371/journal.pone.0024832

Figure 1. Progression of cutaneous lesions in the 108 pfu group.

Figure 1

Day 3: Focal area of mild epidermal hyperplasia and keratinocyte swelling. Day 5: Marked epidermal hyperplasia with ballooning degeneration and early vesicle formation (*). Day 7: Intraepidermal pustule and early crust formation; dermal inflammation is primarily neutrophilic. Day 11: Resolution of epidermal hyperplasia and replacement by large serocellular crust; dermal inflammation is primarily lymphohistiocytic, H&E 10X; mag bars = 50 um.