Table 2. Prevalence of Cardiovascular Diseases and Diabetes Mellitus type 2 across the rs5068 Genotype.
Characteristic | AA (n=1445) |
AG + GG (n=163) |
Odds Ratio (95% CI) [P-value] * |
Odds Ratio (95% CI) [P-value] † |
Odds Ratio (95% CI) [P-value] ‡ |
---|---|---|---|---|---|
Verified Hypertension | 425 (29%) | 47 (29%) | 0.97 (0.68, 1.39) [0.879] | 0.91 (0.63, 1.31) [0.600] | 1.01 (0.69, 1.48) [0.950] |
Coronary artery disease | 185 (13%) | 14 (9%) | 0.64 (0.36, 1.13) [0.124] | 0.57 (0.31, 1.05) [0.071] | 0.61 (0.33, 1.12) [0.109] |
Myocardial Infarction | 80 (6%) | 3 (2%) | 0.32 (0.10, 1.02) [0.055] | 0.29 (0.09, 0.96) [0.042] | 0.32 (0.10, 1.06) [0.061] |
Congestive Heart Failure | 31 (2%) | 5 (3%) | 1.44 (0.55, 3.77) [0.453] | 1.40 (0.52, 3.74) [0.504] | 1.57 (0.58, 4.23) [0.373] |
Atrial Fibrillation | 68 (5%) | 10 (6%) | 1.32 (0.67, 2.63) [0.421] | 1.29 (0.63, 2.64) [0.487] | 1.35 (0.66, 2.77) [0.417] |
Cerebrovascular Accident | 20 (1%) | 4 (2%) | 1.79 (0.61, 5.31) [0.292] | 1.76 (0.59, 5.26) [0.311] | 1.79 (0.60, 5.37) [0.300] |
Diabetes Mellitus type 2 | 108 (7%) | 13 (8%) | 1.07 (0.59, 1.95) [0.818] | 1.05 (0.57, 1.93) [0.875] | 1.26 (0.68, 2.35) [0.459] |
Odds Ratio, 95% CI and P-value obtained from logistic regression univariate model
Odds Ratio, 95% CI and P-value obtained from logistic regression model adjusting for age and gender
Odds Ratio, 95% CI and P-value obtained from logistic regression model adjusting for age, gender and BMI